
I'd love to get a sequel to Astro Boy: Omega Factor from the GBA, which was a fantasic action game from Treasure (really, anything from Treasure would be great these days). Another great one-and-done GBA game was Drill Drozer from Game Freak. Such a fun, unigue game from the folks that normally just pump out Pokémon. I wish they got to do original games more often. I would also love a proper sequel to The Legend of Zelda: Four Sword Adventures. Not a lot of people were able get enough people and Game Boys and link cables together to play that game properly but I've been through that game twice and it is such an awesome multiplayer experience. TriForce Heroes was fun but it played very differently (much more puzzle oriented). Gimme the action focus of Four Swords.
As for MGS2...never played it. The Twin Snakes is my only experience with the series, even though between collections and PS+ I actually have the entire main series now, and I intend to play it. Just need the time...